Procalcitonin-guided therapy for the initiation of antibiotics in the emergency department: a systematic review Yuri van der Does, Pleunie P.M. Rood, Juanita A. Haagsma, Peter Patka, Eric C.M. van Gorp, Maarten Limper
DOI: http://dx.doi.org/10.1016/j.ajem.2016.03.065
Publication stage: In Press Accepted Manuscript
The American Journal of Emergency Medicine
Published online: April 3 2016
x Procalcitonin (PCT) is a new biomarker with a higher accuracy in the diagnosis of bacterial infections. Utilization of PCT may reduce the number of unnecessary antibiotics prescribed to patients, and consequently may decrease the rise in antibiotic resistance. The aim of this systematic review is to determine if a PCT-guided algorithm can safely reduce the number of antibiotics prescribed to all patients with a suspected of infection in the emergency department(ED).
Changing epidemiology and management of infectious diseases in US EDs Amir M. Mohareb, Andrea F. Dugas, Yu-Hsiang Hsieh
DOI: http://dx.doi.org/10.1016/j.ajem.2016.03.024
Publication stage: In Press Corrected Proof
The American Journal of Emergency Medicine
Published online: March 11 2016
x The rise of antibiotic-resistant pathogens is believed to have influenced the emergency department (ED) epidemiology and management of infectious diseases (IDs) since 2000.
Are physicians able to recognition ineffective (agonal) breathing as element of cardiac arrest? Jacek Smereka, Łukasz Szarpak, Łukasz Czyzewski, Dorota Zysko, Adam Smereka
DOI: http://dx.doi.org/10.1016/j.ajem.2016.03.002
Publication stage: In Press Corrected Proof
The American Journal of Emergency Medicine
Published online: March 3 2016
x We have read with great interest the letter by Rottenberg [1] concerning on the absence of gasping upon emergency medical services arrival as a predictor of the need to endotracheal intubation. Agonal breathing is brainstem reflex and the last respiratory pattern that occurs during the early stages of cardiac arrest (CA) [2]. Agonal breathing is defined as ineffective, gasping respirations. Lay persons’ descriptions of agonal breathing are varied and included terms of gasping , wheezing , groaning , snorting , weak breathing , occasional breathing , irregular breathing , and poor breathing [3].
Weight loss surgery and subsequent emergency care use: a population-based cohort study Junaid A. Bhatti, Avery B. Nathens, Deva Thiruchelvam, Donald A. Redelmeier
DOI: http://dx.doi.org/10.1016/j.ajem.2016.02.007
The American Journal of Emergency Medicine , Vol. 34 , Issue 5 ,
Published online: February 12 2016
x This study assessed long-term emergency care utilization after weight loss surgery.
High-flow nasal cannula oxygen supply as treatment in hypercapnic respiratory failure: a case report Victoria Lepere, Jonathan Messika, Béatrice La Combe, Jean-Damien Ricard
DOI: http://dx.doi.org/10.1016/j.ajem.2016.02.020
Publication stage: In Press Corrected Proof
The American Journal of Emergency Medicine
Published online: February 12 2016
x We report the case of a chronic obstructive pulmonary disease (COPD) patient admitted for an acute-on-chronic respiratory failure with hypercapnia, successfully treated with high-flow nasal oxygen cannula.
Presentations of coccidioidomycosis in the ED Andrew Moffat, Frank Lovecchio
DOI: http://dx.doi.org/10.1016/j.ajem.2016.01.025
The American Journal of Emergency Medicine , Vol. 34 , Issue 5 ,
Published online: January 27 2016
x Coccidioidomycosis is a fungal infection found in Arizona, California, New Mexico, Texas, northern Mexico and other areas of similar climate in South America
[1]
. The state of Arizona diagnoses 60% of cases nationwide per year
[3]
. Over the last five years coccidioidomycosis patients have presented to the Maricopa Medical Center Emergency Department in Phoenix, Arizona with a variety of chief complaints. Review of each patient's history revealed several similarities between presentations of the disease.
Tracheal ultrasonography and ultrasonographic lung sliding for confirming endotracheal tube placement: Faster? Reliable? Sinan Karacabey, Erkman Sanrı, Emin Gokhan Gencer, Ozlem Guneysel
DOI: http://dx.doi.org/10.1016/j.ajem.2016.01.027
Publication stage: In Press Corrected Proof
The American Journal of Emergency Medicine
Published online: January 26 2016
x In this study we aimed to evaluate the success of ultrasonography (USG) for confirming the tube placement and timeliness by tracheal USG and ultrasonographic lung sliding in resuscitation and rapid sequence intubation.
The effect of nebulized magnesium sulfate in the treatment of moderate to severe asthma attacks: a randomized clinical trial Shaker Hossein, Akhavan Pegah, Farsi Davood, Abbasi Said, Mahshidfar Babak, Mofidi Mani, Rezai Mahdi, Hafezimoghadam Peyman
DOI: http://dx.doi.org/10.1016/j.ajem.2016.01.024
The American Journal of Emergency Medicine , Vol. 34 , Issue 5 ,
Published online: January 20 2016
x Thirty percent of people with asthma do not respond to standard treatment, and complementary therapies are needed. The objective of this study was to investigate the impact of inhaled magnesium sulfate on the treatment response in emergency department (ED) patients with moderate to severe attacks of asthma.
Admission serum lactate predicts mortality in aneurysmal subarachnoid hemorrhage Imo P. Aisiku, Peng Roc Chen, Hanh Truong, Daniel R. Monsivais, Jonathan Edlow
DOI: http://dx.doi.org/10.1016/j.ajem.2015.12.079
The American Journal of Emergency Medicine , Vol. 34 , Issue 4 ,
Published online: December 30 2015
x Aneurysmal subarachnoid hemorrhage (SAH) is the most devastating form of hemorrhagic stroke. Primary predictors of mortality are based on initial clinical presentation. Initial serum lactic acid levels have been shown to predict mortality and disease severity. Initial serum lactate may be an objective predictor or mortality.
Ketamine-propofol combination (ketofol) vs propofol for procedural sedation and analgesia: systematic review and meta-analysis Mohammad Jalili, Maryam Bahreini, Amin Doosti-Irani, Rasoul Masoomi, Mona Arbab, Hadi Mirfazaelian
DOI: http://dx.doi.org/10.1016/j.ajem.2015.12.074
The American Journal of Emergency Medicine , Vol. 34 , Issue 3 ,
Published online: December 28 2015
x This meta-analysis of trials was conducted to evaluate the analgesic and side effects of ketamine-propofol combination (ketofol) in comparison to propofol in procedural sedation and analgesia (PSA).
How reliable are electrolyte and metabolite results measured by a blood gas analyzer in the ED? Emin Uysal, Yahya Ayhan Acar, Ahmet Kutur, Erdem Cevik, Necati Salman, Onur Tezel
DOI: http://dx.doi.org/10.1016/j.ajem.2015.11.025
The American Journal of Emergency Medicine , Vol. 34 , Issue 3 ,
Published online: November 16 2015
x Blood gas analysis is a frequently ordered test in emergency departments for many indications. It is a rapid technique that can analyze electrolyte and metabolites in addition to pH and blood gases. The aim of this study was to investigate the correlation of electrolyte and metabolite results measured by blood gas and core laboratory analyzers.
Inflammatory biomarkers predicting prognosis in patients with acute dyspnea Karolin Wiklund, Klas Gränsbo, Nathalie Lund, Marjaneh Peyman, Lena Tegner, Maria Toni-Bengtsson, Mattias Wieloch, Olle Melander
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.052
The American Journal of Emergency Medicine , Vol. 34 , Issue 3 ,
Published online: November 9 2015
Open Access x The objective was to identify inflammatory biomarkers that predict risk of 90-day mortality in patients with acute dyspnea.
Respiratory depression in the intoxicated trauma patient: are opioids to blame? Eleni Shenk, Cassie A. Barton, Nathan D. Mah, Ran Ran, Robert G. Hendrickson, Jennifer Watters
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.053
The American Journal of Emergency Medicine , Vol. 34 , Issue 2 ,
Published online: November 3 2015
x Providing effective pain management to acutely intoxicated trauma patients represents a challenge of balancing appropriate pain management with the risk of potential respiratory depression from opioid administration. The objective of this study was to quantify the incidence of respiratory depression in trauma patients acutely intoxicated with ethanol who received opioids as compared with those who did not and identify potential risk factors for respiratory depression in this population. Retrospective medical record review was conducted for subjects identified via the trauma registry who were admitted as a trauma activation and had a detectable serum ethanol level upon admission.
Persistent hiccups followed by acute respiratory failure Yu-Ren Lin, Chang-Chih Shih, Hsiang-Cheng Chen, Sy-Jou Chen
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.042
Publication stage: In Press Corrected Proof
The American Journal of Emergency Medicine
Published online: October 26 2015
x A 19-year-old woman presented with symptoms of persistent and relapsing hiccups for 2 months, followed by a swallowing dysfunction that deteriorated to acute respiratory failure. Brain magnetic resonance imaging showed hyperintense areas in the posterior medulla and left inferior cerebellar peduncle in a T2-weighted image, suggesting demyelinating lesions. Sjogren syndrome was diagnosed based on subsequent positive tests of antinuclear and anti-Ro antibodies as well as salivary scintigraphy examinations.
Plasma bioactive adrenomedullin as a prognostic biomarker in acute heart failure Wesley H. Self, Alan B. Storrow, Oliver Hartmann, Tyler W. Barrett, Gregory J. Fermann, Alan S. Maisel, Joachim Struck, Andreas Bergmann, and others
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.033
The American Journal of Emergency Medicine , Vol. 34 , Issue 2 ,
Published online: October 23 2015
x The objective was to evaluate the prognostic performance of a new biomarker, plasma bioactive adrenomedullin (bio-ADM), for short-term clinical outcomes in acute heart failure.
Acute Care Diagnostics Collaboration: Assessment of a Bayesian clinical decision model integrating the Prehospital Sepsis Score and point-of-care lactate Amado Alejandro Baez, Laila Cochon
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.007
The American Journal of Emergency Medicine , Vol. 34 , Issue 2 ,
Published online: October 18 2015
x Previous research demonstrated that shock index and respiratory rate are highly predictive of intensive care unit admissions.
Appropriateness of epinephrine use in ED patients with anaphylaxis Damian V. Baalmann, John B. Hagan, James T.C. Li, Erik P. Hess, Ronna L. Campbell
DOI: http://dx.doi.org/10.1016/j.ajem.2015.10.003
The American Journal of Emergency Medicine , Vol. 34 , Issue 2 ,
Published online: October 8 2015
x Studies have demonstrated low rates of emergency department (ED) epinephrine administration for anaphylaxis patients, suggestive of ED undertreatment of anaphylaxis. Our study assessed the appropriateness of ED epinephrine administration in anaphylaxis management.
Comparison of chest compression interruption times across 2 automated devices: a randomized, crossover simulation study Jamie L. Estock, Holly K. Curinga, Airan Li, Lorin B. Grieve, Christopher R. Brackney
DOI: http://dx.doi.org/10.1016/j.ajem.2015.09.011
The American Journal of Emergency Medicine , Vol. 34 , Issue 1 ,
Published online: September 19 2015
x The goal of this study was to compare chest compression interruption times required to apply, adjust, and remove 2 different automated chest compression (ACC) devices using the same evaluation protocol.
Use of capnographs to assess quality of pediatric ventilation with 3 different airway modalities Julia Fuzak Freeman, Christopher Ciarallo, Lara Rappaport, Maria Mandt, Lalit Bajaj
DOI: http://dx.doi.org/10.1016/j.ajem.2015.09.012
The American Journal of Emergency Medicine , Vol. 34 , Issue 1 ,
Published online: September 19 2015
x Prehospital pediatric airway management is difficult and controversial. Options include bag-mask ventilation (BMV), endotracheal tube (ETT), and laryngeal mask airway (LMA). Emergency Medical Services personnel report difficulty assessing adequacy of BMV during transport. Capnography, and capnograph tracings in particular, provide a measure of real-time ventilation currently used in prehospital medicine but have not been well studied in pediatric patients or with BMV. Our objective was to compare pediatric capnographs created with 3 airway modalities.
ED crowding and the outcomes of out-of-hospital cardiac arrest Jiwon Kang, Joonghee Kim, You Hwan Jo, Kyuseok Kim, Jae Hyuk Lee, Taeyun Kim, Jungyoup Lee, Ji Eun Hwang, and others
DOI: http://dx.doi.org/10.1016/j.ajem.2015.08.002
The American Journal of Emergency Medicine , Vol. 33 , Issue 11 ,
Published online: August 4 2015
x Emergency department (ED) overcrowding is a worldwide problem associated with adverse outcomes. This study was performed to investigate the association between ED overcrowding and the outcomes and quality of cardiopulmonary resuscitation for out-of-hospital cardiac arrest (OHCA).
