Theophylline concentrations in the emergency treatment of acute bronchial asthma
Charles L. Emerman
,x
, MD†Charles L. Emerman
Search for articles by this author
Affiliations
- Division of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Richard M. Nowak
,x
, MDRichard M. Nowak
Search for articles by this author
Affiliations
- Division of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Correspondence
- Address reprint requests to Richard Nowak, MD, Division of Emergency Medicine, Henry Ford Hospital, W. Grand Boulevard, Detroit, MI 48202, USA

x
Richard M. Nowak
Search for articles by this author
Affiliations
- Division of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Correspondence
- Address reprint requests to Richard Nowak, MD, Division of Emergency Medicine, Henry Ford Hospital, W. Grand Boulevard, Detroit, MI 48202, USA
Michael C. Tomlanovich
,x
, MDMichael C. Tomlanovich
Search for articles by this author
Affiliations
- Division of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Sam Yanari
,x
, PhDSam Yanari
Search for articles by this author
Affiliations
- the Division of Allergy and Immunology, Henry Ford Hospital, Detroit, Michigan, USA.
Diana Sarkar
,x
, MDDiana Sarkar
Search for articles by this author
Affiliations
- Division of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
John A. Anderson
x
, MDJohn A. Anderson
Search for articles by this author
Affiliations
- the Division of Allergy and Immunology, Henry Ford Hospital, Detroit, Michigan, USA.
†Presently with the Department of Emergency Medicine, Cleveland Metropolitan General Hospital, Case Western Reserve University, Cleveland, Ohio.
References
- 1.Mitenko, PA, Ogilvie, RI. Rational intravenous doses of theophylline. N Engl J Med. 1973;289:600–603.
- 2.Josephson, GW, MacKenzie, MS, Lietman, PS et al, Emergency treatment of asthma: A comparison of two treatment regimens. JAMA. 1979;242:639–643.
- 3.Eaton, ML, Green, BA, Church, TR et al, Efficacy of theophylline in “irreversible” airflow obstruction. Ann Intern Med. 1980;92:758–761.
- 4.Rossing, TH, Fanta, CH, Goldstein, DH et al, Emergency therapy of asthma: Comparison of the acute effects of parenteral and inhaled sympathomimetics and infused aminophylline. Am Rev Respir Dis. 1980;122:365–371.
- 5.Fanta, CH, Rossing, TH, McFadden, ER. Emergency room treatment of asthma: Relationships among therapeutic combinations, severity of obstruction and time course of response. Am J Med. 1982;72:416–422.
- 6.in: Chronic bronchitis, asthma and pulmonary emphysema: A statement by the committee on prognostic standards in non-tuberculous respiratory disease. Am Rev Respir Dis. 85. ed. 3. American Thoracic Society,
; 1962:762–768.
- 7.Thompson, RD, Nagasawa, HT, Jenne, JW. Determination of theophylline and its metabolites in human urine and serum by high pressure liquid chromatography. J Lab Clin Med. 1974;84:584–593.
- 8.Broussard, LA. Theophylline determination by “high pressure” liquid chromatography. Clin Chem. 1981;27:1931–1933.
- 9.Nowak, RM, Gordon, KR, Wroblewski, DA et al, Spirometric evaluation of acute bronchial asthma. JACEP. 1979;8:9–12.
- 10.Nowak, RM, Pensler, MI, Sarkar, DD et al, Comparison of peak expiratory flow and FEV1 admission criteria for acute bronchial asthma. Ann Emerg Med. 1982;11:64–69.
- 11.Morris, JF, Koski, A, Johnson, LC. Spirometric standards for healthy non-smoking adults. Am Rev Respir Dis. 1971;103:57–67.
- 12.Cherniack, RM, Raber, MB. Normal standards for venilatory function using an automated wedge spirometer. Am Rev Respir Dis. 1972;106:38–46.
- 13.Eney, DR, Goldstein, EO. Compliance of chronic asthmatics with oral administration of theophylline as measured by serum and salivary levels. Pediatrics. 1976;57:513–517.
- 14.Weinberger, MW, Matthay, RW, Ginchansky, EJ et al, Intravenous aminophylline dosage. JAMA. 1976;235:2110–2113.
- 15.Kordash, TR, Van Dellen, RG, McCall, JT. Theophylline concentrations in asthmatic patients after administration of aminophylline. JAMA. 1977;238:139–141.
- 16.Zwillick, CW, Sutton, FD, Neff, TA et al, Theophylline-induced seizures in adults: Correlation with serum concentrations. Ann Intern Med. 1975;82:784–787.
- 17.Jacobs, MH, Senior, RM, Kessler, G. Clinical experience with theophylline: Relationships between dosage, serum concentration and toxicity. JAMA. 1976;235:1983–1986.
© 1983 Published by Elsevier Inc.
Access this article on
Visit ScienceDirect to see if you have access via your institution.
Article Tools
Related Articles
Searching for related articles..
