Department of Emergency Medicine, Mt. Carmel Mercy Hospital, Detroit, Michigan, USA.
the Division of Emergency Medicine, Michigan State University School of Medicine, East Lansing, Michigan, USA.
Correspondence
Address reprint requests to Dr. White: Section of Emergency Medicine, Michigan State University College of Medicine, A-206-A East Fee Hall, East Lansing, MI 48823.
Department of Emergency Medicine, Mt. Carmel Mercy Hospital, Detroit, Michigan, USA.
the Division of Emergency Medicine, Michigan State University School of Medicine, East Lansing, Michigan, USA.
Correspondence
Address reprint requests to Dr. White: Section of Emergency Medicine, Michigan State University College of Medicine, A-206-A East Fee Hall, East Lansing, MI 48823.
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Abstract
Perfusion of the cerebral cortex (rCCBF) during resuscitation from cardiac arrest was studied using 24 large dogs and three different resuscitation models. Conventional cardiopulmonary resuscitation (CPR) was compared with interposed abdominal compression CPR (IAC-CPR) and with IAC-CPR together with infusion of epinephrine. Conventional CPR produced a mean rCCBF of only 11% (0.057 ± 0.07 ml/min/g) normal perfusion (0.54 ± 0.14 ml/min/g). Even without epinephrine, IAC-CPR produced mean rCCBF equal to 51% (0.27 ± 0.17 ml/min/g) of normal. With epinephrine, IAC-CPR produced rCCBF (0.93 ± 0.49 ml/min/g) statistically indistinguishable from normal. Both models of IAC-CPR were significantly superior to conventional CPR in perfusion of the cerebral cortex.
