This paper is only available as a PDF. To read, Please Download here.
Abstract
Although the highly toxic nature of castor bean (Ricinus communis) is well recognized, reports of human toxicity in the English medical literature
are scarce. The potentially lethal doses reported for children and adults are three
beans and four to eight beans respectively. Recent experience with two cases provides
added insight into the expected course of toxicity. In both cases, repeated vomiting,
diarrhea, and transiently elevated serum creatinine occurred. Dehydration was much
more pronounced in the second case. Both patients recovered uneventfully. Other reported
manifestations of castor bean toxicity, such as hepatic necrosis, renal failure, erythrocyte
hemolysis, convulsions, and shock, did not occur.
Keywords
To read this article in full you will need to make a payment
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D; use, select 'Corporate R&D; Professionals'
Subscribe:
Subscribe to The American Journal of Emergency MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Acute voluntary intoxication by ricin.Hum Toxicol. 1983; 2: 239-242
- Mechanism of action of the toxic lectins abrin and ricin.Nature. 1974; 249: 627-631
- Isolation and comparison of galactose-binding lectins from abrus prectorius and Ricinus communis.J Biol Chem. 1974; 249: 803-810
- Ricin. The toxic protein of castor oil seeds.Toxicology. 1974; 2: 77-102
- Poisindex™. Micromedex, Denver1985
- Ricinus poisoning: A familiar epidemy.Acta Pharmacol Toxicol. 1977; 41 (suppl): 351-361
- Isselbacher Adams RD Braunwald E Harrison's Principles of Internal Medicine. 9th ed. McGraw-Hill Book Company, New York1980: 436-437
Article Info
Publication History
Accepted:
November 20,
1985
Received:
November 7,
1985
Identification
Copyright
© 1986 Published by Elsevier Inc.