This paper is only available as a PDF. To read, Please Download here.
Abstract
Because the benefits from thrombolytic therapy in acute myocardial infarction (AMI)
are time dependent, multiple strategies have been devised to speed therapy. This study
sought to determine whether hospital-based nurse and paramedic advanced life support
(ALS) providers could be trained to independently evaluate (sight read) a prehospital
12-lead electrocardiogram (ECG) for the presence of AMI as part of a protocol designed
to speed in-hospital administration of thrombolytic agents. Providers were required
to determine on the basis of a protocol (1) whether or not AMI was present, and (2)
whether or not thrombolytic therapy was indicated. Providers then radioed their impression
to the emergency department (ED) and initiated a protocol to prepare identified candidates
for thrombolysis. The final decision to initiate thrombolytic therapy was made by
the ED physician after patient arrival at the hospital. One hundred fifty-five patients
with chest pain were studied. Twenty-one (13.5%) were ultimately proven in-hospital
to have AMI. Providers were able to recognize AMI in 17 of 21. Four of 21 did not
meet ECG criteria for AMI on the field ECG, but were categorized as having a high
index of suspicion for AMI by providers. There were no false-positive diagnoses. Fourteen
patients (9%) received thrombolytic therapy. In-hospital times to administration of
thrombolytic therapy decreased to an average of 22 ± 13.8 minutes in the studied group
compared with a historical control group average of 51 ± 50 minutes. It is concluded
that hospital-based paramedics and nurses can successfully be taught to evaluate (ie,
sight read) a prehospital ECG for the presence of AMI with accuracy. A prehospital
chest pain protocol using a field ECG can speed in-hospital administration of thrombolytic
therapy to the extent that field administration of thrombolytic agents may not significantly
improve times to administration of therapy when transport times are similar to those
of this study.
Keywords
To read this article in full you will need to make a payment
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D; use, select 'Corporate R&D; Professionals'
Subscribe:
Subscribe to The American Journal of Emergency MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction: Anglo-Scandinavian study of early thrombolysis (ASSET).Lancet. 1988; 2: 525-530
- Effectivess of intravenous thrombolytic treatment in acute myocardial infarction.Lancet. 1986; 1: 397-402
- Randomized trial of intravenous recombinant tissue-type plasminogen activator versus streptokinase in acute myocardial infarction. ECSG.Lancet. 1985; 1: 842-847
- Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17187 cases of suspected acute myocardial infarction: ISIS-2.Lancet. 1988; 2: 349-360
- Infarct size reduction and preservation of ejection fraction with very early thrombolytic treatment for myocardial infarction; radionuclide results from the Myocardial Infarction Triage and Intervention Trial.Circulation. 1992; 86 ([Abstract]) (suppl 1): 643
- Longterm effects of intravenous thrombolysis in acute myocardial infarction: A final report of the GISSI study.Lancet. 1987; 2: 871-874
- Prevention of myocardial damage in acute myocardial ischemia by early treatment with intravenous streptokinase.N Engl J Med. 1985; 313: 1384-1389
- Importance of early initiation of intravenous streptokinase therapy for acute myocardial infarction.Am J Cardiol. 1986; 58: 411-417
- Time delays in the diagnosis and treatment of acute myocardial infarction: A tale of eight cities.in: Report from the PreHospital Study Group and the Cincinnati Heart Project. 2nd ed. Am Heart J. 120. 1990: 773-780
- Prehospital coronary thrombolysis: A new strategy in acute myocardial infarction.Chest. 1987; 92: 124-128
- Feasibility of prehospital thrombolytic therapy in acute myocardial infarction.Am J Emerg Med. 1986; 4: 201-204
- Achievement of thrombolysis at home in cases of acute myocardial infarction.Lancet. 1987; 1: 228-229
- Prehospital thrombolytic treatment of acute myocardial infarction with anisoylated plasminogen streptokinase activator complex.Crit Care Med. 1988; 16: 823-830
- Prehospital administration of anisoylated plasminogen streptokinase activator complex in acute myocardial infarction.Drugs. 1987; 33: 231-234
- Should thrombolytic therapy be administered in the mobile intensive care unit in patients with evolving myocardial infarction? A pilot study.J Am Coll Cardiol. 1990; 15: 932-936
- Impact of field-transmitted electrocardiography on time to in-hospital thrombolytic therapy in acute myocardial infarction.Am J Cardiol. 1990; 66: 786-791
- Evaluation of patients for the need of thrombolytic therapy in the prehospital setting.Annals Emerg Med. 1989; 18: 483-488
- Prehospital diagnosis and treatment of acute myocardial infarction: A North-South perspective.Am Heart J. 1991; 121: 1-11
- The potential for prehospital thrombolytic therapy.Clin Cardiol. 1990; 13: VIII23-VIII26
- Routine management of acute myocardial infarction; lessons from overviews of recent randomized controlled trials.Circulation. 1990; 82 (suppl 2): 11-17
- Feasibility of prehospital r-TPA therapy in chest pain patients.Ann Emerg Med. 1992; 21: 379-383
- Accuracy of computer-interpreted electrocardiography in selecting patients for thrombolytic therapy.J Am Coll Cardiol. 1991; 17: 1486-1491
- Accuracy of a portable interpretive ECG machine in diagnosis of acute evolving myocardial infarction.Aust N Z J Med. 1992; 22: 9-13
- The dilemma of sensitivity versus specificity in computer-interpreted acute myocardial infarction.J Electrocardol. 1992; 24 (suppl): 2-7
Article Info
Publication History
Accepted:
May 28,
1993
Received:
April 2,
1993
Identification
Copyright
© 1994 Published by Elsevier Inc.