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—Between 60% and 90% of the general population suffers from a headache in any given year. As a direct result of their headaches, 9% to 15% of those afflicted miss days from work or school.1,2 Headache is the chief complaint of 1.3% to 2.5% of all patients presenting to the ED.3,4,5 Studies have shown that anywhere from 1% to 16% of these ED patients have serious pathology.6 It is necessary to quickly recognize and treat these patients to avoid morbidity. We present what appears to be a straightforward case of headache that concludes with the diagnosis of acute bacterial meningitis caused by the unlikely organism Stenotrophomonas maltophilia.

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