Abstract
The aim of this study was to evaluate the effect of thrombolytic therapy on neurologic
outcome and mortality in patients after cardiac arrest due to acute ST-elevation myocardial
infarction and to compare this with those in patients treated with primary percutaneous
coronary intervention (PCI).
We retrospectively examined patients after they had ventricular fibrillation cardiac
arrests. To assess the effect of thrombolysis and PCI on outcome, we used odds ratios
and their 95% confidence intervals and logistic regression modeling.
Thrombolysis was applied in 101 patients (69%) and PCI in 46 patients (31%). More
patients who received thrombolysis had favorable functional neurologic recovery (cerebral
performance category 1 and 2) and survived to 6 months compared with patients with
primary PCI (P = .38 and P = .13, respectively).
In patients with cardiac arrest due to ST-elevation myocardial infarction, it may
be acceptable to use thrombolysis as a reperfusion strategy. This applies especially
in hospitals where immediate PCI is not available.
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Article Info
Publication History
Accepted:
October 24,
2006
Received in revised form:
October 19,
2006
Received:
September 8,
2006
Identification
Copyright
© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
