Reviewer 1: I disagree with the author's concern about clinical features of patients presenting with pulmonary embolism (PE) to the emergency department (ED). I think emergency physicians commonly meet complicated patients with PE because those patients have more serious complaints and they tend to present to EDs rather than hospital polyclinics or the offices of private physicians. Therefore, it is not surprising that these patients revealed serious deviations in vital parameters and elevated cardiac troponin I (cTnI) levels more frequently.