Overtreatment of gonorrhea and chlamydial infections in 2 inner-city emergency departments☆☆☆
Affiliations
- University of Maryland, School of Medicine, Baltimore, MD
Affiliations
- University of Maryland, School of Medicine, Baltimore, MD
Affiliations
- University of Maryland, School of Medicine, Baltimore, MD
Affiliations
- University of Maryland, School of Medicine, Baltimore, MD
Correspondence
- Corresponding author.

Affiliations
- University of Maryland, School of Medicine, Baltimore, MD
Correspondence
- Corresponding author.

Article Info
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Abstract
Background
Infections with Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) are the most commonly reported sexually transmitted diseases in the United States.
Objectives
The primary objective of this study was to estimate the incidence of overtreatment of GC and CT infections in the emergency department (ED). The secondary objective was to determine if there are clinical variables that predict infection with GC and CT.
Methods
A retrospective medical record review was performed at 2 inner-city hospitals. Records were obtained from the evaluation of female patients who presented to the ED between January 1, 2012, and December 31, 2012, who were tested for GC and CT infection. A standardized form was used to extract specific information from each medical record.
Results
Data were extracted from 538 medical records. Of the 522 ED visits, 32 (6%) yielded test results positive for either GC or CT, including 3 that were positive for both. Treatment was administered to 101 patients (19%) and declined by an additional 9 (2%). Of those receiving antibiotics, 87 of 101 (0.86; 95% confidence interval, 0.77-0.92) had negative test results. Of those not offered antibiotics, 17 of 412 (0.04; 95% confidence interval, 0.02-0.07) had positive test results. The overtreatment proportion was similar at hospitals (55/66 [0.83] and 32/35 [0.91], respectively). Of clinical variables that were considered, only age less than 19 years was statistically associated with a positive test result for GC and CT.
Conclusion
The rate of overtreatment for GC and CT was 86%. The practice of empirical treatment should be reconsidered.
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☆We have no conflicts of interest to disclose.
☆☆CH, TVP, and HM conceived the study, designed the study, and obtained research funding. CH, TVP, HM, and MW supervised the data collection. CH, TVP, HM, and GW undertook recruitment of participating centers and patients and managed the data, including quality control. MW provided statistical advice on study design and analyzed the data. CH, TVP, and HM drafted the manuscript; and all authors contributed substantially to its revision. CH, TVP, and HM take responsibility for the paper as a whole.
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