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The first case report of mefloquine-associated rhabdomyolysis

Ivan Comelli
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Ivan Comelli
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Affiliations

  • Emergency Department, Hospital of Piacenza, Piacenza, Italy
,
Giuseppe Lippi
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Giuseppe Lippi
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Affiliations

  • Section of Clinical Biochemistry, University of Verona, Verona, Italy
, MD
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Andrea Magnacavallo
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Andrea Magnacavallo
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Affiliations

  • Emergency Department, Hospital of Piacenza, Piacenza, Italy
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Gianfranco Cervellin
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Gianfranco Cervellin
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Affiliations

  • Emergency Department, Academic Hospital of Parma, Parma, Italy

Correspondence

  • Corresponding author at: Emergency Department, Academic Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy. Tel.: +39 0521 703800; fax: +39 0521 703144.
correspondence
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Gianfranco Cervellin
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Affiliations

  • Emergency Department, Academic Hospital of Parma, Parma, Italy

Correspondence

  • Corresponding author at: Emergency Department, Academic Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy. Tel.: +39 0521 703800; fax: +39 0521 703144.
DOI: http://dx.doi.org/10.1016/j.ajem.2016.03.059

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Background: Direct muscle injury is the most common cause of rhabdomyolysis, but infections, endocrine and metabolic disorders, environmental conditions, and drugs have also been recognized as potential causes. The most common adverse effects of mefloquine, an antimalarial drug, are gastrointestinal, and neurological. Rhabdomyolysis in association with mefloquine has not been previously reported. Case Report: A 36 years old man presented to the ED complaining for malaise, fatigue, and difficulty in performing the usual daily activities.

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© 2016 Published by Elsevier Inc.
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