Cost-effective adenosine dosing for the treatment of PSVT
Affiliations
- Department of Medicine, Brown University School of Medicine, Providence, RI. USA
- From the Department of Emergency Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI. USA
Affiliations
- Department of Medicine, Brown University School of Medicine, Providence, RI. USA
- From the Department of Emergency Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI. USA
Correspondence
- Address reprint requests to Dr Spitalnic, Department of Emergency Medicine, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903.

Affiliations
- Department of Medicine, Brown University School of Medicine, Providence, RI. USA
- From the Department of Emergency Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI. USA
Correspondence
- Address reprint requests to Dr Spitalnic, Department of Emergency Medicine, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903.
Affiliations
- the Department of Surgery, Brown University School of Medicine, Providence, RI. USA
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Abstract
We reviewed our experience with adenosine for the conversion of paroxysmal supraventricular tachycardia (PSVT) to determine whether the recommended dosing strategy of 6 mg, followed by 12 mg, is cost-effective in actual practice. We observed a 65% conversion rate to sinus rhythm with the initial dosage of 6 mg adenosine (95% CI, 54% to 75%), and, based on subsequent cost analysis, conclude that the current strategy should not be replaced by a 12-mg-first strategy. If the packaging of adenosine was changed so that 12 mg cost less than twice 6 mg, this analysis should be revisited.
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