Abdominal pain and lactic acidosis with ethylene glycol poisoning
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Fig. 1
CT scan of the abdomen showing streaks of air in the mesentery and dilated gas filled loops of intestine.
—Ethylene glycol is an organic solvent found in automobile antifreeze and a variety of other commercial products. Easy accessibility and sweet taste has made it a fairly common culprit in overdoses. Despite adequate therapeutic levels of ethanol, even as “pretreatment,” patient can develop severe acidosis with end-organ damage.1 Target organ cellular damage is seen in the kidney, brain, myocardium, pancreas, and blood vessels.2 Ischemic bowel necrosis has never been reported in association with ethylene glycol, although necrosis of bilateral putamen3 and focal hemorrhages in the gastric lining have been reported.
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© 2001 W.B. Saunders Company. Published by Elsevier Inc. All rights reserved.
